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Linkage Disequilibrium Analysis of Biallelic DNA Markers, Human Quantitative Trait Loci, and Threshold-Defined Case and Control Subjects

Linkage disequilibrium (LD) mapping has been applied to many simple, monogenic, overtly Mendelian human traits, with great success. However, extensions and applications of LD mapping approaches to more complex human quantitative traits have not been straightforward. In this article, we consider the...

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Main Authors: Schork, Nicholas J., Nath, Swapan K., Fallin, Daniele, Chakravarti, Aravinda
格式: Artigo
語言:Inglês
出版: The American Society of Human Genetics 2000
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1288563/
https://ncbi.nlm.nih.gov/pubmed/11032785
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