Primary, Nonsyndromic Vesicoureteric Reflux and Its Nephropathy Is Genetically Heterogeneous, with a Locus on Chromosome 1

Primary vesicoureteric reflux (VUR) affects 1%–2% of whites, and reflux nephropathy (RN) causes up to 15% of end-stage renal failure in children and adults. There is a 30–50-fold increased incidence of VUR in first-degree relatives of probands, compared with the general population. We report the res...

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Main Authors: Feather, Sally A., Malcolm, Sue, Woolf, Adrian S., Wright, Victoria, Blaydon, Diana, Reid, Christopher J. D., Flinter, Frances A., Proesmans, Willem, Devriendt, Koen, Carter, Joan, Warwicker, Paul, Goodship, Timothy H. J., Goodship, Judith A.
Format: Artigo
Sprog:Inglês
Udgivet: The American Society of Human Genetics 2000
Fag:
Report
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1288208/
https://ncbi.nlm.nih.gov/pubmed/10739767
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