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Linkage Analysis in the Presence of Errors II: Marker-Locus Genotyping Errors Modeled with Hypercomplex Recombination Fractions
It is well known that genotyping errors lead to loss of power in gene-mapping studies and underestimation of the strength of correlations between trait- and marker-locus genotypes. In two-point linkage analysis, these errors can be absorbed in an inflated recombination-fraction estimate, leaving the...
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| Asıl Yazarlar: | , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
The American Society of Human Genetics
2000
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1288145/ https://ncbi.nlm.nih.gov/pubmed/10712221 |
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