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Haplotype Fine Mapping by Evolutionary Trees

To refine the location of a disease gene within the bounds provided by linkage analysis, many scientists use the pattern of linkage disequilibrium between the disease allele and alleles at nearby markers. We describe a method that seeks to refine location by analysis of “disease” and “normal” haplot...

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Detalles Bibliográficos
Autores principales: Lam, Johnny C., Roeder, Kathryn, Devlin, B.
Formato: Artigo
Lenguaje:Inglês
Publicado: The American Society of Human Genetics 2000
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1288117/
https://ncbi.nlm.nih.gov/pubmed/10677324
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