Variation in the Interleukin 4–Receptor α Gene Confers Susceptibility to Asthma and Atopy in Ethnically Diverse Populations

After a genomewide screen in the Hutterites was completed, the IL4RA gene was examined as the 16p-linked susceptibility locus for asthma and atopy. Seven known variants and one novel variant, representing all nonsynonymous substitutions in the mature protein, were examined in the Hutterites; on the...

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Principais autores: Ober, Carole , Leavitt, Stephanie A. , Tsalenko, Anya , Howard, Timothy D. , Hoki, Danessa M. , Daniel, Rajeev , Newman, Dina L. , Wu, Xiaodong , Parry, Rodney , Lester, Lucille A. , Solway, Julian , Blumenthal, Malcolm , King, Richard A. , Xu, Jianfeng , Meyers, Deborah A. , Bleecker, Eugene R. , Cox, Nancy J. 
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Human Genetics|1 2000
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1288105/
https://ncbi.nlm.nih.gov/pubmed/10677312
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