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The asialoglycoprotein receptor clears glycoconjugates terminating with sialic acidα2,6GalNAc

Endogenous ligands have not, to date, been identified for the asialoglycoprotein receptor (ASGP-R), which is abundantly expressed by parenchymal cells in the liver of mammals. On the basis of the rapid clearance of BSA bearing multiple chemically coupled sialic acid (Sia)α2,6GalNAcβ1,4GlcNAcβ1,2Man...

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Bibliografische gegevens
Hoofdauteurs: Park, Eric I., Mi, Yiling, Unverzagt, Carlo, Gabius, Hans-Joachim, Baenziger, Jacques U.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 2005
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1288006/
https://ncbi.nlm.nih.gov/pubmed/16286643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0508537102
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