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Purkinje cell long-term depression is prevented by T-588, a neuroprotective compound that reduces cytosolic calcium release from intracellular stores

Long-term depression (LTD) of the parallel-fiber (PF) Purkinje synapse induced by four different experimental paradigms could be prevented in rat cerebellar slices by T-588, a neuroprotective compound. The paradigms consisted of pairing PF activation with climbing-fiber activation, direct depolariza...

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Bibliografiske detaljer
Main Authors: Kimura, Tatsuo, Sugimori, Mutsuyuki, Llinás, Rodolfo R.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2005
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1287999/
https://ncbi.nlm.nih.gov/pubmed/16278299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0508190102
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