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Somatic integration of an oncogene-harboring Sleeping Beauty transposon models liver tumor development in the mouse
The Sleeping Beauty (SB) transposon system can integrate foreign sequences of DNA in the genome of mouse somatic cells eliciting long-term expression in vivo. This technology holds great promise for human gene therapy as a nonviral technology to deliver therapeutic genes. SB also provides a means to...
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| Main Authors: | , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
National Academy of Sciences
2005
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1287966/ https://ncbi.nlm.nih.gov/pubmed/16286660 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0502974102 |
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