Complex Segregation Analysis Provides Compelling Evidence for a Major Gene Underlying Obsessive-Compulsive Disorder and for Heterogeneity by Sex

Evidence from twin and family studies supports a genetic etiology for obsessive-compulsive disorder (OCD). The purpose of this study was to test whether a major gene is implicated in a proportion of families with OCD. Complex segregation analyses of 153 families (80 case and 73 control), ascertained...

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Main Authors: Nestadt, G., Lan, T., Samuels, J., Riddle, M., Bienvenu III, O. J., Liang, K. Y., Hoehn-Saric, R., Cullen, B., Grados, M., Beaty, T. H., Shugart, Y. Y.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society of Human Genetics 2000
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1287940/
https://ncbi.nlm.nih.gov/pubmed/11058433
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