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Primary Autosomal Recessive Microcephaly: MCPH5 Maps to 1q25-q32

Primary microcephaly is thought to result from genetic defects of the developmental program that generates large brain hemispheres in humans. Autosomal recessive inheritance is likely in most familial cases, and four loci were recently mapped by homozygosity. We report homozygosity mapping of a new...

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Detalhes bibliográficos
Main Authors: Jamieson, C. Ruth, Fryns, Jean-Pierre, Jacobs, Jos, Matthijs, Gert, Abramowicz, Marc J.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society of Human Genetics 2000
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1287933/
https://ncbi.nlm.nih.gov/pubmed/11067780
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