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Gene Dosage and Linezolid Resistance in Enterococcus faecium and Enterococcus faecalis

Resistance to linezolid has been associated with a G2576U mutation in domain V of the 23S rRNA. We analyzed nine clinical isolates of linezolid-resistant enterococci and showed a clear association between the number of 23S rRNA genes containing this mutation and the level of linezolid resistance exp...

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Bibliographic Details
Published in:Antimicrob Agents Chemother
Main Authors: Marshall, S. H., Donskey, C. J., Hutton-Thomas, R., Salata, R. A., Rice, L. B.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2002
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Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC128780/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12234875/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.46.10.3334-3336.2002
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