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When Coupled to Natural Transformation in Acinetobacter sp. Strain ADP1, PCR Mutagenesis Is Made Less Random by Mismatch Repair

Random PCR mutagenesis is a powerful tool for structure-function analysis of targeted proteins, especially when coupled with DNA integration through natural transformation followed by selection for loss of function. The technique has been applied successfully to structure-function analysis of transc...

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Detalhes bibliográficos
Main Authors: Buchan, Alison, Ornston, L. Nicholas
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1287675/
https://ncbi.nlm.nih.gov/pubmed/16269815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.71.11.7610-7612.2005
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