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−11 Mutation in the ampC Promoter Increasing Resistance to β-Lactams in a Clinical Escherichia coli Strain

A mutation was discovered in the Pribnow box of the ampC promoter in a clinical Escherichia coli strain. This −11 C-to-T transition created a perfect homology with the −10 consensus sequence. The new promoter was cloned upstream of the cat gene of pKK232-8 and induced a sixfold increase in promoter...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Corvec, S., Caroff, N., Espaze, E., Marraillac, J., Reynaud, A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2002
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC128767/
https://ncbi.nlm.nih.gov/pubmed/12234856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.46.10.3265-3267.2002
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