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A Mutation in the First Ligand-Binding Repeat of the Human Very-Low-Density Lipoprotein Receptor Results in High-Affinity Binding of the Single V1 Module to Human Rhinovirus 2

Minor group human rhinoviruses (HRVs) bind members of the low-density lipoprotein receptor family for cell entry. The ligand-binding domains of these membrane proteins are composed of various numbers of direct repeats of about 40 amino acids in length. Residues involved in binding of module 3 (V3) o...

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Autors principals: Nizet, Stephane, Wruss, Juergen, Landstetter, Nathalie, Snyers, Luc, Blaas, Dieter
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2005
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1287599/
https://ncbi.nlm.nih.gov/pubmed/16282473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.23.14730-14736.2005
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