Biological Cost of Rifampin Resistance from the Perspective of Staphylococcus aureus

Resistance determinants that interfere with normal physiological processes in the bacterial cell usually cause a reduction in biological fitness. Fitness assays revealed that 17 of 18 in vitro-selected chromosomal mutations within the rpoB gene accounting for rifampin resistance in Staphylococcus au...

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Bibliographic Details
Main Authors: Wichelhaus, Thomas A., Böddinghaus, Boris, Besier, Silke, Schäfer, Volker, Brade, Volker, Ludwig, Albrecht
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2002
Subjects:
Mechanisms of Resistance
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC128759/
https://ncbi.nlm.nih.gov/pubmed/12384339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.46.11.3381-3385.2002
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