Skin Hyperproliferation and Susceptibility to Chemical Carcinogenesis in Transgenic Mice Expressing E6 and E7 of Human Papillomavirus Type 38

The oncoproteins E6 and E7 of human papillomavirus type 38 (HPV38) display several transforming activities in vitro, including immortalization of primary human keratinocytes. To evaluate the oncogenic activities of the viral proteins in an in vivo model, we generated transgenic mice expressing HPV38...

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Main Authors: Dong, Wen, Kloz, Ulrich, Accardi, Rosita, Caldeira, Sandra, Tong, Wei-Min, Wang, Zhao-Qi, Jansen, Lars, Dürst, Matthias, Sylla, Bakary S., Gissmann, Lutz, Tommasino, Massimo
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2005
Teme:
Transformation and Oncogenesis
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1287566/
https://ncbi.nlm.nih.gov/pubmed/16282489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.23.14899-14908.2005
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