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Homo-Oligomerization of Marburgvirus VP35 Is Essential for Its Function in Replication and Transcription

The nucleocapsid protein VP35 of Marburgvirus, a filovirus, acts as the cofactor of the viral polymerase and plays an essential role in transcription and replication of the viral RNA. VP35 forms complexes with the genome encapsidating protein NP and with the RNA-dependent RNA polymerase L. In additi...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Möller, Peggy, Pariente, Nonia, Klenk, Hans-Dieter, Becker, Stephan
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2005
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1287548/
https://ncbi.nlm.nih.gov/pubmed/16282487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.23.14876-14886.2005
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