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Rare Etiology of Autosomal Recessive Disease in a Child with Noncarrier Parents

A child with maple syrup urine disease type 2 (MSUD2) was found to be homozygous for a 10-bp MSUD2-gene deletion on chromosome 1. Both purported parents were tested, and neither carries the gene deletion. Polymorphic simple-sequence repeat analyses at 15 loci on chromosome 1 and at 16 loci on other...

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Detalhes bibliográficos
Main Authors: Lebo, Roger V., Shapiro, Lawrence R., Fenerci, Elif Yosunkaya, Hoover, J. M., Chuang, Jacinta L., Chuang, David T., Kronn, David F.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society of Human Genetics 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1287534/
https://ncbi.nlm.nih.gov/pubmed/10915611
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