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Characterization of Terminal Deletions at 7q32 and 22q13.3 Healed by De Novo Telomere Addition

We have developed a strategy for the isolation of terminal deletion breakpoints from any chromosome that has been healed by de novo addition of a telomere repeat array. Breakpoints at 7q32 and 22q13.3 have been isolated and characterized in two patients (patients FB336R and AJ). Both truncated chrom...

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Detalhes bibliográficos
Main Authors: Varley, Helen, Di, Shaojie, Scherer, Stephen W., Royle, Nicola J.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society of Human Genetics 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1287521/
https://ncbi.nlm.nih.gov/pubmed/10924407
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