Melanization of Cryptococcus neoformans and Histoplasma capsulatum Reduces Their Susceptibilities to Amphotericin B and Caspofungin

The fungal pathogens Cryptococcus neoformans and Histoplasma capsulatum produce melanin-like pigments in the presence of l-dopa in vitro and during mammalian infection. We investigated whether melanization affected the susceptibilities of the fungi to amphotericin B, caspofungin, fluconazole, itraco...

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Bibliographic Details

Published in:	Antimicrob Agents Chemother
Main Authors:	van Duin, David, Casadevall, Arturo, Nosanchuk, Joshua D.
Format:	Artigo
Language:	Inglês
Published:	American Society for Microbiology (ASM) 2002
Subjects:	Mechanisms of Resistance
Online Access:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC128748/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12384341/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.46.11.3394-3400.2002
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