Expression of SHV-2 β-Lactamase and of Reduced Amounts of OmpK36 Porin in Klebsiella pneumoniae Results in Increased Resistance to Cephalosporins and Carbapenems

A Klebsiella pneumoniae clinical isolate was resistant to cefoxitin, cefotaxime, ceftazidime, ceftazidime-clavulanate, piperacillin-tazobactam (MICs, >256 μg/ml in all cases), and meropenem (MIC, 16 μg/ml) and was intermediate to imipenem (MIC, 8 μg/ml). Decreased expression of the OmpK36 porin and...

詳細記述

書誌詳細

出版年:	Antimicrob Agents Chemother
主要な著者:	Crowley, Brendan, Benedí, Vicente J., Doménech-Sánchez, Antonio
フォーマット:	Artigo
言語:	Inglês
出版事項:	American Society for Microbiology (ASM) 2002
主題:	Mechanisms of Resistance
オンライン･アクセス:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC128712/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12384391/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.46.11.3679-3682.2002
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