TAK1, but not TAB1 or TAB2, plays an essential role in multiple signaling pathways in vivo

TGF-β-activated kinase 1 (TAK1), a member of the MAPKKK family, is thought to be a key modulator of the inducible transcription factors NF-κB and AP-1 and, therefore, plays a crucial role in regulating the genes that mediate inflammation. Although in vitro biochemical studies have revealed the exist...

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Detalhes bibliográficos
Main Authors: Shim, Jae-Hyuck, Xiao, Changchun, Paschal, Amber E., Bailey, Shannon T., Rao, Ping, Hayden, Matthew S., Lee, Ki-Young, Bussey, Crystal, Steckel, Michael, Tanaka, Nobuyuki, Yamada, Gen, Akira, Shizuo, Matsumoto, Kunihiro, Ghosh, Sankar
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2005
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1283960/
https://ncbi.nlm.nih.gov/pubmed/16260493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1360605
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