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TAK1, but not TAB1 or TAB2, plays an essential role in multiple signaling pathways in vivo
TGF-β-activated kinase 1 (TAK1), a member of the MAPKKK family, is thought to be a key modulator of the inducible transcription factors NF-κB and AP-1 and, therefore, plays a crucial role in regulating the genes that mediate inflammation. Although in vitro biochemical studies have revealed the exist...
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| Asıl Yazarlar: | , , , , , , , , , , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Cold Spring Harbor Laboratory Press
2005
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1283960/ https://ncbi.nlm.nih.gov/pubmed/16260493 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1360605 |
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