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Transactivation of Schizosaccharomyces pombe cdt2(+) stimulates a Pcu4–Ddb1–CSN ubiquitin ligase
Cullin-4 forms a scaffold for multiple ubiquitin ligases. In Schizosaccharomyces pombe, the Cullin-4 homologue (Pcu4) physically associates with Ddb1 and the COP9 signalosome (CSN). One target of this complex is Spd1. Spd1 regulates ribonucleotide reductase (RNR) activity. Spd1 degradation during S...
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| Autors principals: | , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group
2005
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1283953/ https://ncbi.nlm.nih.gov/pubmed/16252005 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600854 |
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