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Increased Expression of Clumping Factor and Fibronectin-Binding Proteins by hemB Mutants of Staphylococcus aureus Expressing Small Colony Variant Phenotypes

Small colony variants (SCVs) of Staphylococcus aureus are slow-growing subpopulations that cause persistent and relapsing infections. The altered phenotype of SCV can arise from defects in menadione or hemin biosynthesis, which disrupt the electron transport chain and decrease ATP concentrations. Wi...

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Publicat a:Infect Immun
Autors principals: Vaudaux, Pierre, Francois, Patrice, Bisognano, Carmelo, Kelley, William L., Lew, Daniel P., Schrenzel, Jacques, Proctor, Richard A., McNamara, Peter J., Peters, G., Von Eiff, Christof
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2002
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC128368/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12228267/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.70.10.5428-5437.2002
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