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Crystal structure and RNA binding of the Rpb4/Rpb7 subunits of human RNA polymerase II

The Rpb4 and Rpb7 subunits of eukaryotic RNA polymerase II (RNAP(II)) form a heterodimer that protrudes from the 10-subunit core of the enzyme. We have obtained crystals of the human Rpb4/Rpb7 heterodimer and determined the structure to 2.7 Å resolution. The presence of putative RNA-binding domains...

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Hlavní autoři: Meka, Hedije, Werner, Finn, Cordell, Suzanne C., Onesti, Silvia, Brick, Peter
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2005
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1283528/
https://ncbi.nlm.nih.gov/pubmed/16282592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gki945
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