The architecture of pre-mRNAs affects mechanisms of splice-site pairing

The exon/intron architecture of genes determines whether components of the spliceosome recognize splice sites across the intron or across the exon. Using in vitro splicing assays, we demonstrate that splice-site recognition across introns ceases when intron size is between 200 and 250 nucleotides. B...

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Detaylı Bibliyografya
Asıl Yazarlar: Fox-Walsh, Kristi L., Dou, Yimeng, Lam, Bianca J., Hung, She-pin, Baldi, Pierre F., Hertel, Klemens J.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2005
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1283478/
https://ncbi.nlm.nih.gov/pubmed/16260721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0508489102
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