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The architecture of pre-mRNAs affects mechanisms of splice-site pairing
The exon/intron architecture of genes determines whether components of the spliceosome recognize splice sites across the intron or across the exon. Using in vitro splicing assays, we demonstrate that splice-site recognition across introns ceases when intron size is between 200 and 250 nucleotides. B...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1283478/ https://ncbi.nlm.nih.gov/pubmed/16260721 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0508489102 |
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