Mechanisms regulating tissue-specific polarity of monocarboxylate transporters and their chaperone CD147 in kidney and retinal epithelia

Proton-coupled monocarboxylate transporters (MCT) MCT1, MCT3, and MCT4 form heterodimeric complexes with the cell surface glycoprotein CD147 and exhibit tissue-specific polarized distributions that are essential for maintaining lactate and pH homeostasis. In the parenchymal epithelia of kidney, thyr...

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Bibliographic Details
Main Authors: Deora, Ami A., Philp, Nancy, Hu, Jane, Bok, Dean, Rodriguez-Boulan, Enrique
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2005
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1283422/
https://ncbi.nlm.nih.gov/pubmed/16260747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0504419102
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