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Expression of a calmodulin-binding KCNQ2 potassium channel fragment modulates neuronal M-current and membrane excitability

KCNQ2 and KCNQ3 ion channel pore-forming subunits coassemble to form a heteromeric voltage-gated potassium channel that underlies the neuronal M-current. We and others showed that calmodulin (CaM) binds to specific sequence motifs in the C-terminal domain of KCNQ2 and KCNQ3. We also found that a fus...

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Bibliografische gegevens
Hoofdauteurs: Shahidullah, Mohammad, Santarelli, Lindsey Ciali, Wen, Hua, Levitan, Irwin B.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 2005
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1283421/
https://ncbi.nlm.nih.gov/pubmed/16263935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0503966102
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