Discrete Proteolysis of Focal Contact and Adherens Junction Components in Porphyromonas gingivalis-Infected Oral Keratinocytes: a Strategy for Cell Adhesion and Migration Disabling

Adhesive interactions of cells are critical to tissue integrity. We show that infection with Porphyromonas gingivalis, a major pathogen in the periodontal disease periodontitis, interferes with both cell-matrix and cell-cell adhesion in the oral keratinocyte cell line HOK-16. Thus, infected cells sh...

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Autores principales: Hintermann, Edith, Haake, Susan Kinder, Christen, Urs, Sharabi, Andrew, Quaranta, Vito
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2002
Materias:
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC128337/
https://ncbi.nlm.nih.gov/pubmed/12228316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.70.10.5846-5856.2002
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