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Reliable prediction of transcription factor binding sites by phylogenetic verification
We present a statistical methodology that largely improves the accuracy in computational predictions of transcription factor (TF) binding sites in eukaryote genomes. This method models the cross-species conservation of binding sites without relying on accurate sequence alignment. It can be coupled w...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1283155/ https://ncbi.nlm.nih.gov/pubmed/16286651 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0504201102 |
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