Genetic Immunization Elicits Antigen-Specific Protective Immune Responses and Decreases Disease Severity in Trypanosoma cruzi Infection

Immunity to Trypanosoma cruzi requires elicitation of humoral and cell-mediated immune responses to extracellular trypomastigotes and intracellular amastigotes. In this study, the effectiveness of the T. cruzi trans-sialidase family (ts) genes ASP-1, ASP-2, and TSA-1 as genetic vaccines was assessed...

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Bibliographic Details
Main Authors: Garg, Nisha, Tarleton, Rick L.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2002
Subjects:
Microbial Immunity and Vaccines
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC128309/
https://ncbi.nlm.nih.gov/pubmed/12228281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.70.10.5547-5555.2002
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