Genetic Immunization Elicits Antigen-Specific Protective Immune Responses and Decreases Disease Severity in Trypanosoma cruzi Infection

Immunity to Trypanosoma cruzi requires elicitation of humoral and cell-mediated immune responses to extracellular trypomastigotes and intracellular amastigotes. In this study, the effectiveness of the T. cruzi trans-sialidase family (ts) genes ASP-1, ASP-2, and TSA-1 as genetic vaccines was assessed...

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Detalhes bibliográficos

Publicado no:	Infect Immun
Principais autores:	Garg, Nisha, Tarleton, Rick L.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2002
Assuntos:	Microbial Immunity and Vaccines
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC128309/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12228281/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.70.10.5547-5555.2002
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