The Class A Macrophage Scavenger Receptor Is a Major Pattern Recognition Receptor for Neisseria meningitidis Which Is Independent of Lipopolysaccharide and Not Required for Secretory Responses

Macrophages (Mφ) play a key role in the pathogenesis of invasive meningococcal infections. The roles of two pattern recognition molecules, the Mφ scavenger receptor (SR-A) and Toll-like receptor 4 (TLR-4), have been investigated using bone marrow culture-derived Mφ (BMMφ). Surprisingly, a comparison...

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Main Authors: Peiser, Leanne, de Winther, Menno P. J., Makepeace, Katherine, Hollinshead, Michael, Coull, Philip, Plested, Joyce, Kodama, Tatsuhiko, Richard Moxon, E., Gordon, Siamon
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2002
Teme:
Host Response and Inflammation
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC128305/
https://ncbi.nlm.nih.gov/pubmed/12228258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.70.10.5346-5354.2002
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