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Induction of the Gene Encoding Macrophage Chemoattractant Protein 1 by Orientia tsutsugamushi in Human Endothelial Cells Involves Activation of Transcription Factor Activator Protein 1

Human macrophage chemoattractant protein 1 (MCP-1) is a potent mediator of macrophage migration and therefore plays an essential role in early events of inflammation. In endothelial cells, at least three independent pathways regulate MCP-1 expression by NF-κB and AP-1. Orientia tsutsugamushi causes...

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Detalhes bibliográficos
Main Authors: Cho, Nam-Hyuk, Seong, Seung-Yong, Huh, Myung-Sook, Kim, Na-Hyun, Choi, Myung-sik, Kim, Ik-sang
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC128290/
https://ncbi.nlm.nih.gov/pubmed/12183528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.70.9.4841-4850.2002
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