virB-Mediated Survival of Brucella abortus in Mice and Macrophages Is Independent of a Functional Inducible Nitric Oxide Synthase or NADPH Oxidase in Macrophages

The Brucella abortus virB locus is required for establishing chronic infection in the mouse. Using in vitro and in vivo models, we investigated whether virB is involved in evasion of the bactericidal activity of NADPH oxidase and the inducible nitric oxide synthase (iNOS) in macrophages. Elimination...

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Detalhes bibliográficos
Main Authors: Sun, Yao-Hui, den Hartigh, Andreas B., de Lima Santos, Renato, Adams, L. Garry, Tsolis, Renée M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC128286/
https://ncbi.nlm.nih.gov/pubmed/12183526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.70.9.4826-4832.2002
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