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Immunization with the Chlamydia trachomatis Mouse Pneumonitis Major Outer Membrane Protein by Use of CpG Oligodeoxynucleotides as an Adjuvant Induces a Protective Immune Response against an Intranasal Chlamydial Challenge

Recently, we have shown that a vaccine consisting of a purified preparation of the Chlamydia trachomatis mouse pneumonitis (MoPn) major outer membrane protein (MOMP) and Freund's adjuvant can protect mice against a genital challenge. Here, we wanted to determine if CpG motifs could be used as a...

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Bibliographic Details
Main Authors: Pal, Sukumar, Davis, Heather L., Peterson, Ellena M., de la Maza, Luis M.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2002
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC128273/
https://ncbi.nlm.nih.gov/pubmed/12183524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.70.9.4812-4817.2002
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