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A Chlamydia trachomatis-Specific Th2 Clone Does Not Provide Protection against a Genital Infection and Displays Reduced Trafficking to the Infected Genital Mucosa

A T helper type 1 (Th1) response is essential for resolving genital infections with the mouse pneumonitis biovar of Chlamydia trachomatis (MoPn). However, T-cell-dependent anti-chlamydial antibody is produced and may also contribute to protective immunity. We produced a MoPn-specific CD4 Th2 clone (...

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Pubblicato in:Infect Immun
Autori principali: Hawkins, Raymond A., Rank, Roger G., Kelly, Kathleen A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 2002
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC128225/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12183563/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.70.9.5132-5139.2002
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