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A Chlamydia trachomatis-Specific Th2 Clone Does Not Provide Protection against a Genital Infection and Displays Reduced Trafficking to the Infected Genital Mucosa

A T helper type 1 (Th1) response is essential for resolving genital infections with the mouse pneumonitis biovar of Chlamydia trachomatis (MoPn). However, T-cell-dependent anti-chlamydial antibody is produced and may also contribute to protective immunity. We produced a MoPn-specific CD4 Th2 clone (...

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Main Authors: Hawkins, Raymond A., Rank, Roger G., Kelly, Kathleen A.
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2002
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC128225/
https://ncbi.nlm.nih.gov/pubmed/12183563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.70.9.5132-5139.2002
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