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Roles of p38 Mitogen-Activated Protein Kinase, NF-κB, and Protein Kinase C in Proinflammatory Cytokine mRNA Expression by Human Peripheral Blood Leukocytes, Monocytes, and Neutrophils in Response to Anaplasma phagocytophila

Anaplasma phagocytophila, an obligately intracellular bacterium of granulocytes, causes human granulocytic ehrlichiosis. Within 2 h after addition of A. phagocytophila, interleukin-1β (IL-1β), tumor necrosis factor alpha (TNF-α), and IL-6 mRNAs are induced in human peripheral blood leukocytes (PBLs)...

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Main Authors: Kim, Hyung-Yong, Rikihisa, Yasuko
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2002
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC128199/
https://ncbi.nlm.nih.gov/pubmed/12117921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.70.8.4132-4141.2002
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