High-Level Expression of the Malaria Blood-Stage Vaccine Candidate Plasmodium falciparum Apical Membrane Antigen 1 and Induction of Antibodies That Inhibit Erythrocyte Invasion

Apical membrane antigen 1 (AMA-1) is a highly promising malaria blood-stage vaccine candidate that has induced protection in rodent and nonhuman primate models of malaria. Authentic conformation of the protein appears to be essential for the induction of parasite-inhibitory antibody responses. Here...

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Main Authors: Kocken, Clemens H. M., Withers-Martinez, Chrislaine, Dubbeld, Martin A., van der Wel, Annemarie, Hackett, Fiona, Blackman, Michael J., Thomas, Alan W.
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Microbiology 2002
Ábhair:
Fungal and Parasitic Infections
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC128198/
https://ncbi.nlm.nih.gov/pubmed/12117958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.70.8.4471-4476.2002
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