Defective Hyphal Induction of a Candida albicans Phosphatidylinositol 3-Phosphate 5-Kinase Null Mutant on Solid Media Does Not Lead to Decreased Virulence

A phosphatidylinositol 3-phosphate [PI(3)P] 5-kinase gene (CaFAB1) of the most important human pathogenic yeast, Candida albicans, was cloned and sequenced. An open reading frame was detected which encodes a 2,369-amino-acid protein with a calculated molecular mass of 268 kDa and a relative isoelect...

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Autors principals: Augsten, Martin, Hübner, Claudia, Nguyen, Monika, Künkel, Waldemar, Härtl, Albert, Eck, Raimund
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2002
Matèries:
Fungal and Parasitic Infections
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC128189/
https://ncbi.nlm.nih.gov/pubmed/12117957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.70.8.4462-4470.2002
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