Effects of central administation of probenecid on fevers produced by leukocytic pyrogen and PGE2 in the rabbit.

1. Single intracerebroventricular (I.C.V.) injections of probenecid (PBCD, 0.125--0.5 mg) enhanced and prolonged fever caused by I.V. administration of leukocytic pyrogen (LP) in rabbits resting in neutral (23 degrees C), cold (10 degrees C) and hot (30 degrees C) environments. Similar effects were...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Crawford, I L, Kennedy, J I, Lipton, J M, Ojeda, S R
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1979
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1281510/
https://ncbi.nlm.nih.gov/pubmed/430434
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