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Interleukin-8 Secretion from Mycobacterium tuberculosis-Infected Monocytes Is Regulated by Protein Tyrosine Kinases but Not by ERK1/2 or p38 Mitogen-Activated Protein Kinases

Mycobacterium tuberculosis upregulates NF-κB binding and interleukin-8 (IL-8) gene expression and secretion in primary human monocytes. Inhibition of tyrosine protein kinases but not of ERK1/2 or p38 mitogen-activated protein kinases downregulates tuberculosis-induced IL-8 secretion. The inhibitor g...

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Detalhes bibliográficos
Main Authors: Ameixa, Clara, Friedland, Jon S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC128139/
https://ncbi.nlm.nih.gov/pubmed/12117995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.70.8.4743-4746.2002
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