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Inhibition of Leukocyte Rolling by Nitric Oxide during Sepsis Leads to Reduced Migration of Active Microbicidal Neutrophils

We developed two models of sepsis with different degrees of severity, sublethal and lethal sepsis, induced by cecal ligation and puncture. Lethal sepsis induced by cecal ligation and puncture (L-CLP) resulted in failure of neutrophil migration to the infection site and high mortality. Treatment of s...

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Détails bibliographiques
Auteurs principaux: Benjamim, Claudia Farias, Silva, João Santana, Fortes, Zuleica Bruno, Oliveira, Maria Aparecida, Ferreira, Sérgio Henrique, Cunha, Fernando Queiroz
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2002
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC128083/
https://ncbi.nlm.nih.gov/pubmed/12065501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.70.7.3602-3610.2002
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