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Role of Signal Sequence in Vaccine-Induced Protection against Experimental Coccidioidomycosis

The vaccine efficacy of the gene sequence encoding the signal peptide of the antigen known as antigen 2 or proline-rich antigen (Ag2/PRA), an immunodominant antigen present in the cell wall of the fungal pathogen Coccidioides immitis, was investigated in a murine model of coccidioidomycosis. Express...

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Bibliografiske detaljer
Main Authors: Jiang, Chengyong, Magee, D. Mitchell, Ivey, F. Douglas, Cox, Rebecca A.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2002
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC128064/
https://ncbi.nlm.nih.gov/pubmed/12065493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.70.7.3539-3545.2002
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