Cysteine Protease Activity and Histamine Release from the Human Mast Cell Line HMC-1 Stimulated by Recombinant Streptococcal Pyrogenic Exotoxin B/Streptococcal Cysteine Protease

We constructed the expression vector pSK-SCP containing the streptococcal exotoxin B gene (spe b) which expressed protease activity. We showed that the recombinant streptococcal pyogenic exotoxin B/streptococcal cysteine protease (rSPE B/SCP) was secreted into the culture supernatant of the transfor...

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Detalhes bibliográficos
Main Authors: Watanabe, Yukino, Todome, Yuko, Ohkuni, Hisashi, Sakurada, Shinsaku, Ishikawa, Toshio, Yutsudo, Takashi, Fischetti, Vincent A., Zabriskie, John B.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Molecular Pathogenesis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC128063/
https://ncbi.nlm.nih.gov/pubmed/12065540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.70.7.3944-3947.2002
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