Activation of the Pseudomonas aeruginosa Type III Secretion System Requires an Intact Pyruvate Dehydrogenase aceAB Operon

Pseudomonas aeruginosa clinical cystic fibrosis isolate CHA was mutagenized with Tn5Tc to identify new genes involved in type III secretion system (TTSS)-dependent cytotoxicity toward human polymorphonuclear neutrophils. Among 25 mutants affected in TTSS function, 14 contained the insertion at diffe...

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Main Authors: Dacheux, Denis, Epaulard, Olivier, de Groot, Arjan, Guery, Benoit, Leberre, Rozen, Attree, Ina, Polack, Benoit, Toussaint, Bertrand
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2002
Teme:
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC128050/
https://ncbi.nlm.nih.gov/pubmed/12065547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.70.7.3973-3977.2002
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