Activation of the Pseudomonas aeruginosa Type III Secretion System Requires an Intact Pyruvate Dehydrogenase aceAB Operon

Pseudomonas aeruginosa clinical cystic fibrosis isolate CHA was mutagenized with Tn5Tc to identify new genes involved in type III secretion system (TTSS)-dependent cytotoxicity toward human polymorphonuclear neutrophils. Among 25 mutants affected in TTSS function, 14 contained the insertion at diffe...

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Autores principales: Dacheux, Denis, Epaulard, Olivier, de Groot, Arjan, Guery, Benoit, Leberre, Rozen, Attree, Ina, Polack, Benoit, Toussaint, Bertrand
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2002
Materias:
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC128050/
https://ncbi.nlm.nih.gov/pubmed/12065547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.70.7.3973-3977.2002
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