Localization within a Proline-Rich Antigen (Ag2/PRA) of Protective Antigenicity against Infection with Coccidioides immitis in Mice

Subunits of a proline-rich coccidioidal antigen (Ag2/PRA) of Coccidioides immitis were analyzed by comparison as vaccines in mice. The optimal dose of plasmid vaccine encoding full-length Ag2/PRA was determined to be between 10 and 100 μg. Mice vaccinated with plasmids encoding amino acids (aa) 1 to...

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Bibliographische Detailangaben
Hauptverfasser: Peng, Tao, Shubitz, Lisa, Simons, Julie, Perrill, Robert, Orsborn, Kris I., Galgiani, John N.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2002
Schlagworte:
Fungal and Parasitic Infections
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC128045/
https://ncbi.nlm.nih.gov/pubmed/12065470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.70.7.3330-3335.2002
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