Regulation of Apoptotic c-Jun N-Terminal Kinase Signaling by a Stabilization-Based Feed-Forward Loop

A sequential kinase cascade culminating in activation of c-Jun N-terminal kinases (JNKs) plays a fundamental role in promoting apoptotic death in many cellular contexts. The mechanisms by which this pathway is engaged in response to apoptotic stimuli and suppressed in viable cells are largely unknow...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Xu, Zhiheng, Kukekov, Nikolay V., Greene, Lloyd A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2005
Schlagworte:
Signal Transduction
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1280282/
https://ncbi.nlm.nih.gov/pubmed/16260609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.22.9949-9959.2005
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