Noncytopathogenic Pestivirus Strains Generated by Nonhomologous RNA Recombination: Alterations in the NS4A/NS4B Coding Region

Several studies have demonstrated that cytopathogenic (cp) pestivirus strains evolve from noncytopathogenic (noncp) viruses by nonhomologous RNA recombination. In addition, two recent reports showed the rapid emergence of noncp Bovine viral diarrhea virus (BVDV) after a few cell culture passages of...

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Autores principales: Gallei, Andreas, Orlich, Michaela, Thiel, Heinz-Juergen, Becher, Paul
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2005
Materias:
Genetic Diversity and Evolution
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1280241/
https://ncbi.nlm.nih.gov/pubmed/16254361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.22.14261-14270.2005
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