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A Single Amino Acid Change in Rabies Virus Glycoprotein Increases Virus Spread and Enhances Virus Pathogenicity

Several rabies virus (RV) vaccine strains containing an aspartic acid (Asp) or glutamic acid (Glu) instead of an arginine (Arg) at position 333 of the RV glycoprotein (G) are apathogenic for immunocompetent mice even after intracranial inoculation. However, we previously showed that the nonpathogeni...

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書誌詳細
主要な著者: Faber, Milosz, Faber, Marie-Luise, Papaneri, Amy, Bette, Michael, Weihe, Eberhard, Dietzschold, Bernhard, Schnell, Matthias J.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology 2005
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC1280225/
https://ncbi.nlm.nih.gov/pubmed/16254349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.22.14141-14148.2005
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