A Single Amino Acid Change in Rabies Virus Glycoprotein Increases Virus Spread and Enhances Virus Pathogenicity

Several rabies virus (RV) vaccine strains containing an aspartic acid (Asp) or glutamic acid (Glu) instead of an arginine (Arg) at position 333 of the RV glycoprotein (G) are apathogenic for immunocompetent mice even after intracranial inoculation. However, we previously showed that the nonpathogeni...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Faber, Milosz, Faber, Marie-Luise, Papaneri, Amy, Bette, Michael, Weihe, Eberhard, Dietzschold, Bernhard, Schnell, Matthias J.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology 2005
Pynciau:
Pathogenesis and Immunity
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC1280225/
https://ncbi.nlm.nih.gov/pubmed/16254349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.22.14141-14148.2005
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